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Ethical approval processes for animal research are increasingly rigorous, demanding robust demonstration of 3Rs integration and transparent planning. This service supports labs and institutions to build clear, defensible strategies around replacement, reduction, and refinement.
Who it's for
Who it's for
This service is designed for research teams and institutions working with in vivo models who seek to embed the 3Rs into experimental design, project licence applications, and institutional policy. Typical clients include:
Research teams preparing new project licence (PPL) applications or significant amendments requiring enhanced 3Rs justification
Institutions seeking to improve the effectiveness, credibility, and strategic alignment of their Animal Welfare and Ethical Review Bodies (AWERBs)
Groups developing grant applications to funders with high expectations of 3Rs integration and non-animal methodology (e.g. NC3Rs, MRC, EU Framework)
Programme leads, core facilities or platforms aiming to embed refinement, reduction, or replacement practices across research teams
What’s Included
What’s Included
Initial Consultation: Context gathering and review of experimental objectives, current protocols, and institutional priorities.
Format: 1-hour online consultation
Alternatives Mapping: Review of current and emerging non-animal methods and reduced-use approaches relevant to your model or target.
Format: Annotated literature summary + discussion memo
3Rs Integration Strategy: Co-development of a strategy to align experimental design with 3Rs principles, incorporating refinement technologies and statistical power considerations.
Format: 2-hour workshop + editable outline document
Ethics Documentation Support: Review and drafting support for AWERB or Home Office-facing materials, including justifications and welfare protocols.
Format: Markup of draft documents + review meeting
Optional Peer Feedback: Simulated ethical review panel or internal peer review feedback to refine final submission.
Format: 1.5-hour feedback session + summary memo
Outcomes
Outcomes
More robust PPL applications demonstrating embedded 3Rs thinking
Clearer internal and external alignment with evolving 3Rs policies and expectations
Improved confidence and consistency in AWERB review and documentation
Practical outputs that support licensing, peer review, and institutional reputational assurance
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